CSE Mains Medical Science Syllabus

Paper-I consists of seven units: (i) Human Anatomy, (ii) Human Physiology, (iii) Biochemistry, (iv) Pathology, (v) Microbiology, (vi) Pharmacology, (vii) Forensic Medicine and Toxicology.

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Paper-II consists of six units: (i) General Medicine, (ii) Pediatrics, (iii) Dermatology, (iv) General Surgery, (v) Obstetrics and Gynaecology including Family Planning, (vi) Community Medicine.

Paper I

1. Human Anatomy

Applied anatomy including blood and nerve supply of upper and lower limbs and joints of shoulder, hip and knee.

Gross anatomy, blood supply and lymphatic drainage of tongue, thyroid, mammary  gland, stomach, liver, prostate, gonads and uterus.

Applied anatomy of diaphragm, perineum and inguinal region.

Clinical anatomy of kidney, urinary bladder, uterine tubes, vas deferens.

Embryology: Placenta and placental barrier. Development of heart, gut, kidney,  uterus, ovary, testis and their common congenital abnormalities.

Central and Peripheral Autonomic Nervous System: Gross and clinical anatomy of ventricles of brain, circulation of cerebrospinal fluid; Neural pathways and lesions of cutaneous sensations, hearing and vision; Cranial nerves, distribution and  clinical significance; Components of autonomic nervous system.

2. Human Physiology

Conduction and transmission of impulse, mechanism of contraction, neuromuscular transmission, reflexes, control of equilibrium, posture and muscle tone, descending  pathways, functions of cerebellum, basal ganglia, Physiology of sleep and  consciousness.

Endocrine System: Mechanism of action of hormones, formation, secretion, transport,  metabolism, function and regulation of secretion of pancreas and pituitary gland.

Physiology of Reproductive System: Menstrual cycle, lactation, pregnancy.

Blood: Development, regulation and fate of blood cells.

Cardio-vascular, cardiac output, blood pressure, regulation of cardiovascular functions.

3. Biochemistry

Organ function tests - liver, kidney, thyroid Protein synthesis.

Vitamins and minerals.

Restriction fragment length polymorphism (RFLP).

Polymerase chain reaction (PCR).

Radio - immunoassays (RIA). 

4. Pathology

Inflammation and repair, disturbances of growth and cancer, Pathogenesis and histopathology of rheumatic and ischemic  heart disease and diabetes mellitus.

Differentiation between benign, malignant,  primary and metastatic malignancies, Pathogenesis and histopathology of bronchogenic carcinoma, carcinoma breast, oral cancer, cancer cervix, leukemia, Etiology, pathogenesis and histopathology of - cirrhosis liver, glomerulonephritis, tuberculosis, acute osteomyelitis.

5. Microbiology

Humoral and cell mediated immunity.

Diseases caused by and laboratory diagnosis of:

  • Meningococcus, Salmonella
  • Shigella, Herpes, Dengue, Polio
  • HIV/AIDS, Malaria, E. Histolytica,  Giardia
  • Candida, Cryptococcus, Aspergillus

6. Pharmacology

Mechanism of action and side effects of the following drugs:

  • Antipyretics and analgesics, Antibiotics
  • Antimalaria; Antikala-azar, Antidiabetics
  • Antihypertensive, Antidiuretics, General and  cardiac vasodilators, Antiviral, Antiparasitic, Antifungal, Immunosuppressants
  • Anticancer

7. Forensic Medicine and Toxicology

Forensic examination of injuries and wounds; Examination of blood and seminal stains; poisoning, sedative overdose, hanging, drowning, burns, DNA and finger print study.

Paper II

1. General Medicine

Etiology, clinical features, diagnosis and principles of management (including prevention) of - Tetanus, Rabies, AIDS, Dengue, Kala-azar, Japanese Encephalitis.

Etiology, clinical features, diagnosis and principles of management of: Ischaemic heart disease, pulmonary embolism. Bronchial asthma.

Pleural effusion, tuberculosis, Malabsorption syndromes, acid peptic diseases, Viral hepatitis and cirrhosis of liver.

Glomerulonerphritis and pyelonephritis, renal failure, nephrotic syndrome, renovascular hypertension, complications of diabetes mellitus, coagulation disorders, leukemia, Hypo and hyper thyrodism, meningitis  and encephalitis.

Imaging in medical problems, ultrasound, echocardiogram, CT scan, MRI.

Anxiety and Depressive Psychosis and schizophrenia and ECT.

2. Pediatrics

Immunization, Baby friendly hospital, congenital cyanotic heart disease, respiratory distress syndrome, broncho - pneumonias, kernicterus. IMNCI classification and management, PEM grading and management.  ARI and Diarrhea of under five and their management.

3. Dermatology

Psoriasis, Allergic dermatitis, scabies, eczema, vitiligo, Stevan Johnson's syndrome, Lichen Planus.

4. General Surgery

Clinical features, causes, diagnosis and principles of management of cleft palate, harelip.

Laryngeal tumor, oral and esophageal  tumors.

Peripheral arterial diseases, varicose  veins, coarctation of aorta

Tumors of Thyroid, Adrenal Glands

Abscess, cancer, fibroadenoma and adenosis of breast.

Bleeding peptic ulcer, tuberculosis of bowel, ulcerative colitis, cancer stomach.

Renal mass, cancer Prostate.

Haemothorax, stones of Gall bladder, Kidney, Ureter and Urinary Bladder.

Management of surgical conditions of Rectum, Anus and Anal canal, Gall bladder and Bile ducts

 Splenomegaly, cholecystitis, portal hypertension, liver abscess, peritonitis, carcinoma head of pancreas.

Fractures of spine, Colles' fracture and bone tumors.

Endoscopy

Laprascopic Surgery.

5. Obstetrics and Gynaecology including Family Planning

Diagnosis of pregnancy.

Labour management, complications of 3rd stage, Antepartum and postpartum hemorrhage, resuscitation of the newborn, Management of abnormal lie and difficult labour, Management of small for date or premature newborn.

Diagnosis and management of anemia. Preeclampsia and Toxaemias of pregnancy, Management of Post menopausal Syndrome.

Intra-uterine devices, pills, tubectomy and vasectomy. Medical termination of pregnancy including legal aspects.

Cancer cervix.

Leucorrhoea, pelvic pain, infertility, dysfunctional uterine bleeding (DUB), amenorrhoea, Fibroid and prolapse of uterus.

6. Community Medicine (Preventive and Social Medicine)

Principles, methods, approach and measurements of Epidemiology

Nutrition, nutritional diseases / disorders & Nutrition Programmes.

Health information Collection, Analysis and Presentation.

Objectives, components and critical analysis of National programmes for control/ eradication of: Malaria, Kala-azar, Filaria and Tuberculosis, HIV/AIDS, STDs and Dengue

Critical appraisal of Health care delivery system.

Health management and administration: Techniques, Tools, Programme Implementation and Evaluation.

Objective, Component, Goals and Status of Reproductive and Child Health, National Rural Health Mission and Millennium Development Goals

Management of hospital and industrial waste.